Code No: A0307
Jawaharlal Nehru Technological University Hyderabad
M.Tech I Semester Supplementary Examinations September-2009
Time: 3 Hours      Max. Marks: 60
Answer any Five Questions
All Questions Carry Equal Marks

1. a] What are the different methods by which human beings attain immunity.
b] How would you distinguish between active and passive immunity?

2. a] Differentiate between T and B lymphocytes.
b] Write a note on agglutination reaction.

3. a] Explain the role of HLA in transplantation.
b] What is immunological tolerance?

4. a] Describe the structure of an immunoglobulin.
b] What are the different classes of immunoglobulins?
5.  Write short notes on
a) Abzymes
b) Chimeric antibodies
c) Interleukins.

6. a] What is the role of peripheral lymphoid organs.
b] Describe the technique of ELISA.

7. a] How are recombinant vaccines produced? What are their applications?
b] What are the properties of anti idiotypic vaccines?

8. a] Describe the production and applications of monoclonal antibodies.
b] What are the general properties of an antigen- antibody interaction?


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