PGECET Syllabus | PGECET Pharmacy (PY) Syllabus
PGECET Syllabus for Pharmacy :
Pharmacognosy & Phytochemistry: Chemistry of natural products, tests, isolation, purification &characterization and estimation of phytopharmaceuticals belonging to the group of Alkaloids, Glycosides, Terpenoids, Steroids, Bioflavanoids, Purines,lipids, proteins. Pharmacognosy of crude drugs and herbal products. Standardization of raw materials. Modern techniques used for evaluation.
Pharmaceutical Chemistry: Structure, nomenclature, classification, synthesis, SAR and metabolism of the following category of drugs, which are official in Indian Pharmacopoeia and British Pharmacopoeia. Introduction to drug design. Stereochemistry of drug molecules. Hypnotics and Sedatives, Analgesics, NSAIDS, Neuroleptics, Antidepressants, Anxiolytics, Anticonvulsants, Antihistaminics, Local Anaesthetics, Cardio Vas- cular drugs – Antianginal agents Vasodilators, Adrenergic & Cholinergic drugs, Cardiotonic agents, Diuretics, Antijypertensive drugs, Hypoglycemic agents, Antilipedmic agents, Coagulants, Anticoagulants, Antlplatelet agents.Chemotherapeutic agents – Antibiotics, Antibacterials, Sulphadrugs. Antiproliozoal drugs, Antiviral, Antituber- cular, Antimalarial, Anticancer, Antiamoebic drugs. Diagnostic agents..
Pharmaceutics: Formulation, Development and Storage of different dosage forms and new drug delivery systems. Biopharmaceutics and Pharmacokinetics and their importance in Pharmaceutical calculations. Study of physical properties of drugs: Particle size and shape, pKa, solubility, partition coefficient, crystallinity, polymor- phism and hygroscopicity. Study of chemical properties of drugs: Hydrolysis, oxidation, reduction, recimization, polymerization and their influence on formulation and stability of drug products.
Pharmacology: General pharmacological principles including Toxicology. Drug interaction and Pharmacology of drugs acting on Central nervous system, Cardiovascular system, Autonomic nervous system, Gastro intestinal system and Respiratory system. Pharmacology of Autocoids, chemotherapeutic agents including anticancer drugs, Bioassays, Immuno Pharmacology. Drugs acting on the blood & blood forming organs. Clinical Pharmacy Therapeutic Drug Monitoring Dosage regimen in Renal and hepatitic impairment. Drug – Drug interactions and Drug -food interactions, Adverse Drug reactions. Medication History, interview and Patient counseling
Pharmaceutical Analysis and quality assurance: Concepts of qualitative and quantitative analysis, fundamentals of volumetric analysis, methods-of expressing concentration, primary and secondary standards; concept of error, precision, accuracy, specificity, sensitivity, detection limit, linearity and range. Ruggedness, standards, standardization, calibration of analytical equipments. Principles, instrumentation and applications of the fo llowing: Absorption spectroscopy (UV,visible & IR ) .Fluorimetry, Fla me photometry, Potentiometry.Conductometry and Plarography. Pharmacopoeial assays and chromatography methods.Quality assurance and quality control methods, concepts of GMP and GLP and forensic pharmacy.
Pharmaceutical Biotechnology: Isolation, classification and taxonomy of microorganisms. Pure culture techniques, theory and practice of sterilization, microbial growth phases and kinetics, microbial transformation of steroids. Fermentation technology- batch and continuous fermentation. General characteristics and manufacture of antibiotics, vaccines and harmones. Application and scope of recombinant DNA technology in manufacture of biological products such as insuline and human growth harmones. Biochemical role of hormones, Vitamins, Enzymes, Nucleic acids, Metobolic path.ways-glycolosis and TCA cycle and transport across cell membranes.
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